Article
High leptin level and leptin receptor Lys656Asn variant are risk factors for preeclampsia.
Genetics and molecular research : GMR - 15 Jul 2013
Wang S, Qiao F Y, Feng L
Abstract excerpt
The aim of this study was to investigate the relationship between the leptin receptor (LEPR) polymorphism/serum leptin level and preeclampsia. The prevalence of a single nucleotide polymorphism in the LEPR gene exon 14 at -656 and the serum leptin concentrations in 97 preeclamptic pregnant mothers were compared to those of 110 healthy controls. The Lys656Asn genotype and Lys656Asn + Asn656Asn frequencies in the...
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