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Article

Leptin receptor gene polymorphisms c.668A>G and c.1968G>C in Sudanese women with preeclampsia: a case-control study.

BMC medical genetics - 17 Aug 2020

Saad Amira, Adam Ishag, Elzaki Salah Eldin G, Awooda Hiba A, Hamdan Hamdan Z

Abstract excerpt

BACKGROUND: Leptin receptor gene (LEPR) variants may affect the leptin levels and act as a risk factor for preeclampsia. Two LEPR gene missense variants rs1137101 (c.668A>G) and rs1805094 (c.1968G>C) were investigated in Sudanese women with preeclampsia. METHODS: A matched case-control study (122 women in each arm) was conducted in Saad Abualila Maternity Hospital in Khartoum, Sudan from May to December 2018. The...

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Identifiers

PMID: 32807109
DOI: 10.1186/s12881-020-01104-z
PMCID: PMC7433111

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