Article
Association between genetic polymorphisms of leptin receptor and preeclampsia in Chinese women.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Dec 2023
Zeng Shuai, Wu Yujie, Zhou Mi, Bai Huai, Liu Xinghui, Fan Ping
Abstract excerpt
OBJECTIVE: Leptin signaling plays an important role in regulating metabolism and reproduction. In the present study, we investigated the relationship between polymorphisms of leptin receptor (LEPR) gene A223G and A668G and preeclampsia (PE) and evaluated influences of genotypes on clinical, metabolic, and oxidative stress indices in Chinese women. METHODS: This is a case-control study including 322 patients with...
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