Article
Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome.
The EMBO journal - 20 Oct 2010
Inagaki Soichi, Miura-Kamio Asuka, Nakamura Yasukazu, Lu Falong, Cui Xia, Cao Xiaofeng, Kimura Hiroshi, Saze Hidetoshi, Kakutani Tetsuji
Abstract excerpt
In diverse eukaryotes, constitutively silent sequences, such as transposons and repeats, are marked by methylation at histone H3 lysine 9 (H3K9me). Although selective H3K9me is critical for maintaining genome integrity, mechanisms to exclude H3K9me from active genes remain largely unexplored. Here, we show in Arabidopsis that the exclusion depends on a histone demethylase gene, IBM1 (increase in BONSAI...
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