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Article

The (15)N isotope effect as a means for correlating phenotypic alterations and affected pathways in a trait anxiety mouse model.

Proteomics - 1 Aug 2012

Filiou Michaela D, Webhofer Christian, Gormanns Philipp, Zhang Yaoyang, Reckow Stefan, Bisle Birgit, Teplytska Larysa, Frank Elisabeth, Kessler Melanie S, Maccarrone Giuseppina, Landgraf Rainer, Turck Christoph W

Abstract excerpt

Stable isotope labeling techniques hold great potential for accurate quantitative proteomics comparisons by MS. To investigate the effect of stable isotopes in vivo, we metabolically labeled high anxiety-related behavior (HAB) mice with the heavy nitrogen isotope (15)N. (15)N-labeled HAB mice exh...

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Identifiers

PMID: 22700377
DOI: 10.1002/pmic.201100673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22700377-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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