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Article

A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.

Nature communications - 28 May 2015

Ahmad Omar S, Morris John A, Mujammami Muhammad, Forgetta Vincenzo, Leong Aaron, Li Rui, Turgeon Maxime, Greenwood Celia M T, Thanassoulis George, Meigs James B, Sladek Robert, Richards J Brent

Abstract excerpt

In observational studies, type-2 diabetes (T2D) is associated with an increased risk of coronary heart disease (CHD), yet interventional trials have shown no clear effect of glucose-lowering on CHD. Confounding may have therefore influenced these observational estimates. Here we use Mendelian randomization to obtain unconfounded estimates of the influence of T2D and fasting glucose (FG) on CHD risk. Using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26017687
DOI: 10.1038/ncomms8060
PMCID: PMC4458864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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