Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dose-response relationship between genetically proxied average blood glucose levels and incident coronary heart disease in individuals without diabetes mellitus.

Diabetologia - 1 Apr 2021

Burgess Stephen, Malik Rainer, Liu Bowen, Mason Amy M, Georgakis Marios K, Dichgans Martin, Gill Dipender

Abstract excerpt

AIMS/HYPOTHESIS: Our aim was to investigate the relationship between average blood glucose levels and incident CHD in individuals without diabetes mellitus. METHODS: To investigate average blood glucose levels, we studied HbA1c as predicted by 40 variants previously shown to be associated with both type 2 diabetes and HbA1c. Linear and non-linear Mendelian randomisation analyses were performed to investigate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Blood Glucose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Disease

Share to Glycated Hemoglobin

Share to Incidence

Share to Mendelian Randomization Analysis

Share to Time Factors

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 33495845
DOI: 10.1007/s00125-020-05377-0
PMCID: PMC7940279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dose-response relationship between genetically proxied average blood glucose levels and incident coronary heart disease in individuals without diabetes mellitus.PMID 33495845Read ↗

Assessing the linear and non-linear association of HbA1c with cardiovascular disease: a Mendelian randomisation studySemantic proximity Read ↗

Efficacy of metformin targets on cardiometabolic health in the general population and non-diabetic individuals: a Mendelian randomization study.Semantic proximity Read ↗

A 19-SNP coronary heart disease gene score profile in subjects with type 2 diabetes: the coronary heart disease risk in type 2 diabetes (CoRDia study) study baseline characteristics.Semantic proximity Read ↗

Lifestyle modifies the diabetes-related metabolic risk, conditional on individual genetic differencesSemantic proximity Read ↗

Mendelian randomization analysis supports the causal role of dysglycaemia and diabetes in the risk of coronary artery disease.Semantic proximity Read ↗

Genetically Predicted Type 2 Diabetes Mellitus Liability, Glycated Hemoglobin and Cardiovascular Diseases: A Wide-Angled Mendelian Randomization Study.Semantic proximity Read ↗

Differentiating Associations of Glycemic Traits With Atherosclerotic and Thrombotic Outcomes: Mendelian Randomization Investigation.Semantic proximity Read ↗

Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study.Semantic proximity Read ↗

Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization studySemantic proximity Read ↗

Lifestyle Modifies the Diabetes-Related Metabolic Risk, Conditional on Individual Genetic DifferencesSemantic proximity Read ↗

The Impact of Glycated Hemoglobin (HbA1c) on Cardiovascular Disease Risk: A Mendelian Randomization Study Using UK Biobank.Semantic proximity Read ↗

The relationship between repeated measurements of HbA1c and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.