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Article

Mendelian randomization analysis supports the causal role of dysglycaemia and diabetes in the risk of coronary artery disease.

European heart journal - 14 Jun 2015

Ross Stephanie, Gerstein Hertzel C, Eikelboom John, Anand Sonia S, Yusuf Salim, Paré Guillaume

Abstract excerpt

INTRODUCTION: Type 2 diabetes is a strong risk factor for coronary artery disease (CAD). However, the absence of a clear reduction in CAD by intensive glucose lowering in randomized controlled trials has fuelled uncertainty regarding the causal role of dysglycaemia and CAD. OBJECTIVE: To assess whether Mendelian randomization supports a causal role of dysglycaemia and diabetes for risk of CAD. METHODS: Effect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25825043
DOI: 10.1093/eurheartj/ehv083

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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