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Article

Multicolor super-resolution DNA imaging for genetic analysis.

Nano letters - 11 Jul 2012

Baday Murat, Cravens Aaron, Hastie Alex, Kim Hyeongjun, Kudeki Deren E, Kwok Pui-Yan, Xiao Ming, Selvin Paul R

Abstract excerpt

Many types of cancer and neurodegenerative diseases are caused by abnormalities and variations in the genome. We have designed a high-resolution imaging technique with high throughput and low cost for determining structural variations of genes related to genetic diseases. We initially mapped all seven nicking sites of Nb.BbvCI endonuclease enzyme on lambda DNA. Then we resolved densely labeled patterns of 107...

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Identifiers

PMID: 22698062
DOI: 10.1021/nl302069q
PMCID: PMC3880789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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