Article

Large-scale structural variation detection in subterranean clover subtypes using optical mapping validated at nucleotide level

2017-12-11

Abstract excerpt

Whole genome sequencing has been widely used to detect structural variations (SVs). However, the limited single molecule size makes it difficult to characterize large-scale SVs in a genome because they cannot fully cover such vast and complex regions. Recently, optical mapping in nanochannels has provided novel resolution to detect large-scale SVs by comparing the physical location of the nickase recognition seque...

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Literature Corpus work: 536cc33c-8aa1-5058-914a-68f24544e1b8
DOI: 10.1101/232132

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