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In vivo breast cancer characterization imaging using two monoclonal antibodies activatably labeled with near infrared fluorophores

17 Apr 2012

Abstract excerpt

INTRODUCTION: The gene expression profiles of cancer cells are closely related to their aggressiveness and metastatic potential. Antibody-based immunohistochemistry (IHC) of tissue specimens is a common method of identifying expressed proteins in cancer cells and increasingly inform treatment decisions. Molecular imaging is a potential method of performing similar IHC studies in vivo without the requirement for...

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PMID: 22510481
DOI: 10.1186/bcr3167

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