Article
Brain amyloid and cognition in Lewy body diseases.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2012
Gomperts Stephen N, Locascio Joseph J, Marquie Marta, Santarlasci Andrea L, Rentz Dorene M, Maye Jacqueline, Johnson Keith A, Growdon John H
Abstract excerpt
Many patients with PD develop PD with dementia (PDD), a syndrome that overlaps clinically and pathologically with dementia with Lewy bodies (DLB); PDD and DLB differ chiefly in the relative timing of dementia and parkinsonism. Brain amyloid deposition is an early feature of DLB and may account, in part, for its early dementia. We sought to confirm this hypothesis and also to determine whether amyloid accumulation...
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