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Article

Correlation between decreased CSF α-synuclein and Aβ₁₋₄₂ in Parkinson disease.

Neurobiology of aging - 1 Jan 2015

Buddhala Chandana, Campbell Meghan C, Perlmutter Joel S, Kotzbauer Paul T

Abstract excerpt

Accumulation of misfolded α-synuclein (α-syn) protein in Lewy bodies and neurites is the cardinal pathologic feature of Parkinson disease (PD), but abnormal deposition of other proteins may also play a role. Cerebrospinal fluid (CSF) levels of proteins known to accumulate in PD may provide insight into disease-associated changes in protein metabolism and their relationship to disease progression. We measured CSF...

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Identifiers

PMID: 25212463
DOI: 10.1016/j.neurobiolaging.2014.07.043
PMCID: PMC4268043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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