Article
The locus for an inherited cataract in sheep maps to ovine chromosome 6.
Molecular vision - 1 Jan 2012
Wilson Gareth R S, Morton James D, Palmer David N, McEwan John C, Gately Karl, Anderson Rayna M, Dodds Ken G
Abstract excerpt
PURPOSE: Cataracts are an important cause of blindness in humans but there are few large animal models available. One of these animal models is Ovine Heritable Cataract, a bilateral cortical cataract which develops after birth. This cataract has been used as a model for human cataracts in drug trials, but the gene responsible for the cataract trait is unknown. A genetic test for cataract would improve the...
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