Article
Identification of mutations in HSF4 in dogs of three different breeds with hereditary cataracts.
Veterinary ophthalmology - 1 Jan 2000
Mellersh Cathryn S, Pettitt Louise, Forman Oliver P, Vaudin Mark, Barnett Keith C
Abstract excerpt
Cataracts are a leading cause of blindness in both dogs and humans. Mutations in several genes have been associated with inherited forms of human cataract, but no mutations have been identified as the cause of any form of canine inherited cataract. We have used a candidate gene approach to investigate 20 genes, known to be associated with cataract in humans, for their potential association with the development of...
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