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Article

A new locus for autosomal dominant cataract on chromosome 19: linkage analyses and screening of candidate genes.

Investigative ophthalmology & visual science - 1 Aug 2006

Bateman J Bronwyn, Richter Leslie, Flodman Pamela, Burch Douglas, Brown Sandra, Penrose Philip, Paul Otis, Geyer David D, Brooks David G, Spence M Anne

Abstract excerpt

PURPOSE: To map and identify the mutated gene for autosomal dominant cataract (ADC) in family ADC4. METHODS: Ophthalmic evaluations were performed on an American family with ADC and a panel of polymorphic DNA sequence-tagged site (STS) markers for known ADC loci and other genome-wide polymorphic markers were used to map the gene; two-point lod scores were calculated. Fine mapping was undertaken in the chromosomal...

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Share to Chromosomes, Human, Pair 19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16877414
DOI: 10.1167/iovs.05-1035

Genes

DMPK
LIM2
SIX5
FTL
MIP
STS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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