Article
Equine Multiple Congenital Ocular Anomalies maps to a 4.9 megabase interval on horse chromosome 6.
BMC genetics - 19 Dec 2008
Andersson Lisa S, Juras Rytis, Ramsey David T, Eason-Butler Jessica, Ewart Susan, Cothran Gus, Lindgren Gabriella
Abstract excerpt
BACKGROUND: Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome consists of a diverse set of abnormalities predominantly localized to the frontal part of the eye. The disease is in agreement with a codominant mode of inheritance in our horse material. Animals presumed to be heterozygous for the mutant allele have cysts originating from the temporal ciliary body, peripheral retina and/or iris. In contrast,...
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