Article
A novel locus on canine chromosome 13 is associated with cataract in the Australian Shepherd breed of domestic dog.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2015
Ricketts Sally L, Pettitt Louise, McLaughlin Bryan, Jenkins Christopher A, Mellersh Cathryn S
Abstract excerpt
Hereditary cataract is a common ocular disorder in the purebred dog population and is a leading cause of visual impairment and blindness in dogs. Despite this, little is known to date about the genetics underlying this condition. We have used a genome-wide association study and targeted resequencing approach to identify a novel locus for cataracts in the Australian Shepherd breed of dog, using dogs that are clear...
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