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Article

Identification of a major locus for age-related cortical cataract on chromosome 6p12-q12 in the Beaver Dam Eye Study.

Proceedings of the National Academy of Sciences of the United States of America - 5 Oct 2004

Iyengar Sudha K, Klein Barbara E K, Klein Ronald, Jun Gyungah, Schick James H, Millard Christopher, Liptak Rachel, Russo Karlie, Lee Kristine E, Elston Robert C

Abstract excerpt

Age-related cataracts are one of the leading causes of visual impairment and blindness among the elderly worldwide. Among age-related cataracts, cortical opacities rank as the second most common type; however, little is known about their molecular pathogenesis or genetics. To identify susceptibility loci for cortical cataracts, we genotyped a subset of families (102 families; n = 224 sib pairs) from the Beaver...

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Identifiers

PMID: 15452352
DOI: 10.1073/pnas.0400778101
PMCID: PMC521942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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