Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia

12 Jul 2011

Abstract excerpt

BACKGROUND: The EVI1 gene (3q26) codes for a zinc finger transcription factor with important roles in both mammalian development and leukemogenesis. Over-expression of EVI1 through either 3q26 rearrangements, MLL fusions, or other unknown mechanisms confers a poor prognosis in acute myeloid leukemia. DESIGN AND METHODS: We analyzed the prevalence and prognostic impact of EVI1 over-expression in a series of 476...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Blood disorders and treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21750091
DOI: 10.3324/haematol.2011.040535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemiaPMID 21750091Read ↗

Global Identification of EVI1 Target Genes in Acute Myeloid LeukemiaSemantic proximity Read ↗

EVI1 dysregulation: impact on biology and therapy of myeloid malignancies.Semantic proximity Read ↗

High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patientsSemantic proximity Read ↗

High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities.Semantic proximity Read ↗

EVI1 expression in acute myeloid leukaemiaSemantic proximity Read ↗

EVI1 recruits the histone methyltransferase SUV39H1 for transcription repressionSemantic proximity Read ↗

EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemiaSemantic proximity Read ↗

EVI1-mediated Programming of Normal and Malignant HematopoiesisSemantic proximity Read ↗

Expression of EVI1 in myelodysplastic syndromes and other hematologic malignancies without 3q26 translocationsSemantic proximity Read ↗

EVI1 drives leukemogenesis through aberrant ERG activationSemantic proximity Read ↗

[EVI1 expression, clinical and cytogenetical characteristics in 447 patients with acute myeloid leukemia].Semantic proximity Read ↗

EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.