Article
Structure of a murine norovirus NS6 protease-product complex revealed by adventitious crystallisation.
PloS one - 1 Jan 2012
Leen Eoin N, Baeza Gabriela, Curry Stephen
Abstract excerpt
Murine noroviruses have emerged as a valuable tool for investigating the molecular basis of infection and pathogenesis of the closely related human noroviruses, which are the major cause of non-bacterial gastroenteritis. The replication of noroviruses relies on the proteolytic processing of a large polyprotein precursor into six non-structural proteins (NS1-2, NS3, NS4, NS5, NS6(pro), NS7(pol)) by the...
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