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Article

Structural Biology of the Arterivirus nsp11 Endoribonucleases.

Journal of virology - 1 Jan 2017

Zhang Manfeng, Li Xiaorong, Deng Zengqin, Chen Zhenhang, Liu Yang, Gao Yina, Wu Wei, Chen Zhongzhou

Abstract excerpt

Endoribonuclease (NendoU) is unique and conserved as a major genetic marker in nidoviruses that infect vertebrate hosts. Arterivirus nonstructural protein 11 (nsp11) was shown to have NendoU activity and play essential roles in the viral life cycle. Here, we report three crystal structures of porcine reproductive and respiratory syndrome virus (PRRSV) and equine arteritis virus (EAV) nsp11 mutants. The structures...

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Identifiers

PMID: 27795409
DOI: 10.1128/JVI.01309-16
PMCID: PMC5165224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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