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Article

Norovirus Protease Structure and Antivirals Development.

Viruses - 14 Oct 2021

Zhao Boyang, Hu Liya, Song Yongcheng, Patil Ketki, Ramani Sasirekha, Atmar Robert L, Estes Mary K, Prasad B V Venkataram

Abstract excerpt

Human norovirus (HuNoV) infection is a global health and economic burden. Currently, there are no licensed HuNoV vaccines or antiviral drugs available. The protease encoded by the HuNoV genome plays a critical role in virus replication by cleaving the polyprotein and is an excellent target for developing small-molecule inhibitors. The current strategy for developing HuNoV protease inhibitors is by targeting the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34696498
DOI: 10.3390/v13102069
PMCID: PMC8537771

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