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Article

Interferon-gamma (IFN-γ) intronic variant (rs2430561) is a risk factor for systemic lupus erythematosus: Observation from a meta-analysis.

Lupus - 1 Feb 2023

Sarangi Surjyapratap, Nahak Suraj K, Padhi Sunali, Pradhan Bidyutprabha, Nayak Nisha, Pati Abhijit, Panda Aditya K

Abstract excerpt

BACKGROUND: The role of interferon-gamma (IFN-γ) in autoimmune disorders has been well documented. Elevated levels of IFN-γ are observed in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) and are linked with disease severity. Single nucleotide polymorphism in the intronic region of the IFN-γ gene (+874 T>A rs2430561) has been associated with susceptibility to the development of RA and SLE;...

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Source

Identifiers

PMID: 36537753
DOI: 10.1177/09612033221146700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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