Article
Distinctive frequencies of +874T/A IFN-γ gene polymorphism in a healthy Serbian population.
Clinical and translational science - 1 Dec 2012
Popadic Dusan, Savic Emina, Spuran Zorica, Markovic Milos, Mostarica Stojkovic Marija, Ramic Zorica, Pravica Vera
Abstract excerpt
PURPOSE: Single nucleotide polymorphism (SNP) in IFN-γ gene (+874T/A) that determines high (TT), low (AA), and intermediate (TA) responder phenotypes has shown associations with susceptibility to infectious and chronic inflammatory diseases, as well as disease outcome. Therefore, the susceptibility to and outcome of certain diseases can vary in different ethnic populations partially due to the notable differences...
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