Article
SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype.
Journal of molecular cell biology - 1 Dec 2012
Raghoebir Lalini, Bakker Elvira R M, Mills Jason C, Swagemakers Sigrid, Kempen Marjon Buscop-van, Munck Anne Boerema-de, Driegen Siska, Meijer Dies, Grosveld Frank, Tibboel Dick, Smits Ron, Rottier Robbert J
Abstract excerpt
Various factors play an essential role in patterning the digestive tract. During development, Sox2 and Cdx2 are exclusively expressed in the anterior and the posterior parts of the primitive gut, respectively. However, it is unclear whether these transcription factors influence each other in dete...
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