Article
Mannose-binding lectin codon 54 gene polymorphism and vulvovaginal candidiasis: a systematic review and meta-analysis.
BioMed research international - 1 Jan 2014
Nedovic Bojan, Posteraro Brunella, Leoncini Emanuele, Ruggeri Alberto, Amore Rosarita, Sanguinetti Maurizio, Ricciardi Walter, Boccia Stefania
Abstract excerpt
Mannose-binding lectin (MBL) plays a key role in the human innate immune response. It has been shown that polymorphisms in the MBL2 gene, particularly at codon 54 (variant allele B; wild-type allele designated as A), impact upon host susceptibility to Candida infection. This systematic review and meta-analysis were performed to assess the association between MBL2 codon 54 genotype and vulvovaginal candidiasis...
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