Article
A time for reappraisal of "atypical" hemolytic uremic syndrome: should all patients be treated the same?
European journal of pediatrics - 1 Oct 2012
Ruebner Rebecca L, Kaplan Bernard S, Copelovitch Lawrence
Abstract excerpt
UNLABELLED: Atypical hemolytic uremic syndrome (HUS) refers to the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury in the absence of Shiga toxin-producing Escherichia coli exposure or Streptococcus pneumoniae infection. Currently, approximately 50 % of the atypical cases have demonstrable mutations in complement regulatory proteins. Historically, the diagnosis of atypical HUS...
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