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Article

How I diagnose and treat atypical hemolytic uremic syndrome

2 Nov 2022

Abstract excerpt

Our understanding and management of atypical hemolytic uremic syndrome (aHUS) have dramatically improved in the last decade. aHUS has been established as a prototypic disease resulting from a dysregulation of the complement alternative C3 convertase. Subsequently, prospective nonrandomized studies and retrospective series have shown the efficacy of C5 blockade in the treatment of this devastating disease. C5...

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PMID: 36322940
DOI: 10.1182/blood.2022017860

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