Genetic variation in galectin-3 gene associates with cognitive function at old age.

doi:10.1016/j.neurobiolaging.2012.05.001

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Article

Genetic variation in galectin-3 gene associates with cognitive function at old age.

Neurobiology of aging - 1 Sept 2012

Trompet Stella, Jukema Wouter, Mooijaart Simon P, Ford Ian, Stott David J, Westendorp Rudi G J, de Craen Anton J M

Abstract excerpt

Inflammation plays an important role in the development of cognitive decline and dementia in old age. Galectin-3 is known for its role in acute and chronic inflammation. We assessed whether genetic variation in the LGALS3 gene, encoding for galectin-3, associates with cognitive function in the 5804 participants of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). The rs4644, rs4652, and...

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Identifiers

PMID: 22673112
DOI: 10.1016/j.neurobiolaging.2012.05.001

Genes

LGALS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.