Article
Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study.
The journals of gerontology. Series A, Biological sciences and medical sciences - 13 Jul 2020
Miller Lindsay M, Jenny Nancy S, Rawlings Andreea M, Arnold Alice M, Fitzpatrick Annette L, Lopez Oscar L, Odden Michelle C
Abstract excerpt
BACKGROUND: The importance of systemic inflammation, measured by C-reactive protein, in cognitive decline has been demonstrated; however, the role of vascular inflammation is less understood. Pentraxin 3 (PTX3) is a novel marker of vascular inflammation. METHODS: We followed adults 65 and older, free of cardiovascular disease (CVD) for up to 9 years (n = 1,547) in the Cardiovascular Health Study. We evaluated the...
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