Virulence of Shiga Toxin-Producing Escherichia coli (STEC) in Orally-Infected Mice Correlates with the Type of Toxin Produced by the Infecting Strain

Abstract excerpt

In this chapter, we will provide a brief review of the attributes of the Shiga toxin (Stx) family with emphasis on the importance of these toxins in the pathogenesis of disease caused by E. coli O157: H7 and other Shiga toxin-producing E. coli (STEC).We will also describe a modification of our streptomycin (str)-treated, orally-infected mouse model (23, 24) that permits the assessment of the relative virulence of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Clostridium difficile and Clostridium perfringens research
• Share to Escherichia coli research studies
• Share to Viral gastroenteritis research and epidemiology