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Bacterial Genetic Determinants of Non‐O157 STEC Outbreaks and Hemolytic‐Uremic Syndrome after Infection

22 Aug 2006

Abstract excerpt

Although O157:H7 Shiga toxin-producing Escherichia coli (STEC) are the predominant cause of hemolytic-uremic syndrome (HUS) in the world, non-O157:H7 serotypes are a medically important cause of HUS that are underdetected by current diagnostic approaches. Because Shiga toxin is necessary but not sufficient to cause HUS, identifying the virulence determinants that predict severe disease after non-O157 STEC...

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PMID: 16941350
DOI: 10.1086/506620

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