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Relevance of Bacteriophage 933W in the Development of Hemolytic Uremic Syndrome (HUS)

13 Dec 2018

Abstract excerpt

Hemolytic uremic syndrome (HUS) is associated to infections with Shiga-toxin-producing Escherichia coli (STEC). Shiga toxins (Stxs) are known as the principal responsible for HUS development. We previously report Stx2 expression by host cells in vitro and in vivo. Due to the genes encoding the two subunits of Stx are located in the genomes of bacteriophages, the aim of this study was to evaluate the role of...

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PMID: 30619183
DOI: 10.3389/fmicb.2018.03104

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