Article
Genomic islands of uropathogenic Escherichia coli contribute to virulence.
Journal of bacteriology - 1 Jun 2009
Lloyd Amanda L, Henderson Tiffany A, Vigil Patrick D, Mobley Harry L T
Abstract excerpt
Uropathogenic Escherichia coli (UPEC) strain CFT073 contains 13 large genomic islands ranging in size from 32 kb to 123 kb. Eleven of these genomic islands were individually deleted from the genome, and nine isogenic mutants were tested for their ability to colonize the CBA/J mouse model of ascending urinary tract infection. Three genomic island mutants (Delta PAI-aspV, Delta PAI-metV, and Delta PAI-asnT) were...
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