Article
Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli.
Microbiology (Reading, England) - 1 Apr 2006
Holden Nicola J, Totsika Makrina, Mahler Eva, Roe Andrew J, Catherwood Kirsteen, Lindner Karin, Dobrindt Ulrich, Gally David L
Abstract excerpt
The majority of Escherichia coli strains isolated from urinary tract infections have the potential to express multiple fimbriae. Two of the most common fimbrial adhesins are type 1 fimbriae and pyelonephritis-associated pili (Pap). Previous research has shown that induced, plasmid-based expression of a Pap regulator, papB, and its close homologues can prevent inversion of the fim switch controlling the expression...
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