Article
Increased pro-inflammatory cytokine production after lipopolysaccharide stimulation in patients with X-linked agammaglobulinemia.
Journal of clinical immunology - 1 Oct 2012
González-Serrano María Edith, Estrada-García Iris, Mogica-Martínez Dolores, González-Garay Alejandro, López-Herrera Gabriela, Berrón-Ruiz Laura, Espinosa-Padilla Sara Elva, Yamazaki-Nakashimada Marco Antonio, Vargas-Hernández Alexander, Santos-Argumedo Leopoldo, Estrada-Parra Sergio Antonio, Espinosa-Rosales Francisco J
Abstract excerpt
PURPOSE: To evaluate the lipopolysaccharide (LPS)-induced pro-inflammatory cytokine response by peripheral blood mononuclear cells (PBMCs) from XLA patients. METHODS: Thirteen patients with XLA were included in the study. LPS-induced TNF-α, IL-1β, IL-6, and IL-10 production was determined in PBMCs from patients and matched healthy controls by ELISA. Cytokine production was correlated with the severity of...
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