Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type I and III Interferon Productions Are Impaired in X-Linked Agammaglobulinemia Patients Toward Poliovirus but Not Influenza Virus.

Frontiers in immunology - 1 Jan 2018

Luk Anderson Dik Wai, Ni Ke, Wu Yuet, Lam Kwok-Tai, Chan Koon-Wing, Lee Pamela P, Tu Wenwei, Mao Huawei, Lau Yu Lung

Abstract excerpt

Background: X-linked agammaglobulinemia (XLA) is a primary immunodeficiency caused by Bruton's tyrosine kinase (BTK) mutation. Patients are susceptible to severe enterovirus infections. The underlying mechanism remains unknown. BTK is involved in toll-like receptors pathway, which initiates antiviral responses including interferon (IFN) productions. Objective: To demonstrate type I and III IFN productions in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agammaglobulinaemia Tyrosine Kinase
Share to Agammaglobulinemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Diseases, X-Linked

Share to Influenza A Virus, H1N1 Subtype

Share to Interferon Type I

Share to Poliomyelitis

Share to Poliovirus

Share to Toll-Like Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 30147693
DOI: 10.3389/fimmu.2018.01826
PMCID: PMC6095995

Genes

BTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type I and III Interferon Productions Are Impaired in X-Linked Agammaglobulinemia Patients Toward Poliovirus but Not Influenza Virus.PMID 30147693Read ↗

Bruton tyrosine kinase mediates TLR9-dependent human dendritic cell activation.Semantic proximity Read ↗

[Clinical features of X-linked agammaglobulinemia: analysis of 8 cases].Semantic proximity Read ↗

T Cell Abnormalities in X-Linked Agammaglobulinaemia: an Updated Review.Semantic proximity Read ↗

Potential role of type I interferon in the pathogenic process leading to type 1 diabetesSemantic proximity Read ↗

Outcomes of X-Linked Agammaglobulinaemia Patients.Semantic proximity Read ↗

Enterovirus Exposure Uniquely Discriminates Type 1 Diabetes Patients with a Homozygous from a Heterozygous Melanoma Differentiation-Associated Protein 5/Interferon Induced with Helicase C Domain 1 A946T Genotype.Semantic proximity Read ↗

Increased pro-inflammatory cytokine production after lipopolysaccharide stimulation in patients with X-linked agammaglobulinemia.Semantic proximity Read ↗

Haematopoietic Stem Cell Transplant for Norovirus-Induced Intestinal Failure in X-linked AgammaglobulinemiaSemantic proximity Read ↗

X-Linked Agammaglobulinemia With Chronic Meningoencephalitis: A Diagnostic Challenge.Semantic proximity Read ↗

Recurrent pneumonia with mild hypogammaglobulinemia diagnosed as X-linked agammaglobulinemia in adults.Semantic proximity Read ↗

RIG-I– and MDA5-Initiated Innate Immunity Linked With Adaptive Immunity Accelerates β-Cell Death in Fulminant Type 1 DiabetesSemantic proximity Read ↗

Type I IFN Signaling on Both B and CD4 T Cells Is Required for Protective Antibody Response to AdenovirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.