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Article

Engineering of a novel Ca²⁺-regulated kinesin molecular motor using a calmodulin dimer linker.

Biochemical and biophysical research communications - 29 Jun 2012

Shishido Hideki, Maruta Shinsaku

Abstract excerpt

The kinesin-microtubule system holds great promise as a molecular shuttle device within biochips. However, one current barrier is that such shuttles do not have "on-off" control of their movement. Here we report the development of a novel molecular motor powered by an accelerator and brake system, using a kinesin monomer and a calmodulin (CaM) dimer. The kinesin monomer, K355, was fused with a CaM target peptide...

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Identifiers

PMID: 22664103
DOI: 10.1016/j.bbrc.2012.05.135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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