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Article

PTEN signaling in autism spectrum disorders.

Current opinion in neurobiology - 1 Oct 2012

Zhou Jing, Parada Luis F

Abstract excerpt

PTEN germline mutations are found in a small subset of children diagnosed with autism spectrum disorder (ASD) and accompanying macrocephaly. In this review, we discuss recent advances that offer insight into the pathogenesis of this subgroup of autism patients. We provide an overview of how disrupting PTEN function influences neuronal cells, and describe efforts to decipher the cellular mechanisms associated with...

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Source

Identifiers

PMID: 22664040
DOI: 10.1016/j.conb.2012.05.004

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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