Article
Unprovoked atrial tachyarrhythmias in aging spontaneously hypertensive rats: the role of the autonomic nervous system.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2012
Scridon Alina, Gallet Clément, Arisha Moussa M, Oréa Valérie, Chapuis Bruno, Li Na, Tabib Alain, Christé Georges, Barrès Christian, Julien Claude, Chevalier Philippe
Abstract excerpt
Experimental models of unprovoked atrial tachyarrhythmias (AT) in conscious, ambulatory animals are lacking. We hypothesized that the aging, spontaneously hypertensive rat (SHR) may provide such a model. Baseline ECG recordings were acquired with radiotelemetry in eight young (14-wk-old) and eight aging (55-wk-old) SHRs and in two groups of four age-matched Wistar-Kyoto (WKY) rats. Quantification of AT and heart...
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