Article

Abnormal autonomic regulation of heart rate underlies age-related and sex dependent cardiac dysfunction in the small primate Microcebus murinus

2025-12-02

Abstract excerpt

Ageing is a major risk factor for cardiovascular disease associated with the decline of maximal heart rate (HR) and HR variability (HRV). Such a decline could reduce cardiac adaptability to physiological needs and increase susceptibility to arrhythmias. The small primate Grey Mouse Lemur ( Microcebus murinus ), is a valuable model of ageing because it spontaneously develops neurodegenerative diseases. Moreover, i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 08b5d83a-3b5e-55ed-9ab9-fd040ac67d8e
DOI: 10.64898/2025.12.01.691505

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Abnormal autonomic regulation of heart rate underlies age-related and sex dependent cardiac dysfunction in the small primate Microcebus murinusDOI 10.64898/2025.12.01.691505Read

Mouse lemur, a new animal model to investigate cardiac pacemaker activity in primatesSemantic proximity Read

Rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice.Semantic proximity Read

Aging Changes in Bladder Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Are Associated With Increasing Heterogeneity of Adrenergic/Mucosal Influence on Detrusor Control in the Mouse.Semantic proximity Read

Establishing Comprehensive Transthoracic Echocardiography Reference Ranges for Mouse Models: Insights into the Impact of Anesthesia, Sex, and AgeSemantic proximity Read

Phenotypic screening for heart rate variability in the mouse.Semantic proximity Read

The dynamic range of biologic functions and variation of many environmental cues may be declining in the modern age: implications for diseases and therapeutics.Semantic proximity Read

Unique neurophysiologic characteristics of the longest-living rodent: the naked mole ratsSemantic proximity Read

Phenotyping small animals as models for the human metabolic syndrome: thermoneutrality matters.Semantic proximity Read

The influence of captivity on cardiac structure and function across age, in rhesus macaquesSemantic proximity Read

The Healthy Heart: Lessons from Nature's Elite AthletesSemantic proximity Read

Subtle alterations in breathing and heart rate control in the 5-HT1A receptor knockout mouse in early postnatal development.Semantic proximity Read

Does Calorie Restriction in Primates Increase Lifespan? Revisiting Studies on Macaques (Macaca mulatta) and Mouse Lemurs (Microcebus murinus)Semantic proximity Read