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Antibody Affinity Maturation by Computational Design.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Kuroda Daisuke, Tsumoto Kouhei

Abstract excerpt

The immune systems protect our bodies from foreign molecules or antigens, where antibodies play important roles. Antibodies evolve over time upon antigen encounter by somatically mutating their genome sequences. The end result is a series of antibodies that display higher affinities and specificities to specific antigens. This process is called affinity maturation. Recent improvements in computer hardware and...

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PMID: 30196490
DOI: 10.1007/978-1-4939-8648-4_2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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