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Article

KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility.

PLoS genetics - 1 Jan 2012

Smith Lee B, Milne Laura, Nelson Nancy, Eddie Sharon, Brown Pamela, Atanassova Nina, O'Bryan Moira K, O'Donnell Liza, Rhodes Danielle, Wells Sara, Napper Diane, Nolan Patrick, Lalanne Zuzanna, Cheeseman Michael, Peters Josephine

Abstract excerpt

Spermatogenesis is a complex process reliant upon interactions between germ cells (GC) and supporting somatic cells. Testicular Sertoli cells (SC) support GCs during maturation through physical attachment, the provision of nutrients, and protection from immunological attack. This role is facilitated by an active cytoskeleton of parallel microtubule arrays that permit transport of nutrients to GCs, as well as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infertility, Male

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Source

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Identifiers

PMID: 22654668
DOI: 10.1371/journal.pgen.1002697
PMCID: PMC3359976

Genes

KATNAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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