Article
Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort.
Journal of affective disorders - 1 Sept 2010
Lavebratt Catharina, Aberg Elin, Sjöholm Louise K, Forsell Yvonne
Abstract excerpt
BACKGROUND: Genetic variations in FKBP5, BDNF, P2RX7 and CACNA1 are current candidates for involvement in depression. METHODS: The single nucleotide polymorphisms FKBP5:rs1360780, BDNF:rs6265 (Val66Met), P2RX7:2230912 (Gln460Arg) and CACNA1C:rs1006737 were genotyped in DNA from 457 depression cases (major depression, dysthymia, and mixed anxiety depression) and 2286 healthy controls with no symptom of...
Read the complete abstract on PubMed