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Article

Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease.

Neurobiology of aging - 1 Jan 2013

Rapic Sara, Backes Heiko, Viel Thomas, Kummer Markus P, Monfared Parisa, Neumaier Bernd, Vollmar Stefan, Hoehn Mathias, Van der Linden Annemie, Heneka Michael T, Jacobs Andreas H

Abstract excerpt

In Alzheimer's disease (AD), persistent microglial activation as sign of chronic neuroinflammation contributes to disease progression. Our study aimed to in vivo visualize and quantify microglial activation in 13- to 15-month-old AD mice using [(11)C]-(R)-PK11195 and positron emission tomography...

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Identifiers

PMID: 22651996
DOI: 10.1016/j.neurobiolaging.2012.04.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22651996-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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