Article
Unidentified genetic variants influence pancreatic cancer risk: an analysis of polygenic susceptibility in the PanScan study.
Genetic epidemiology - 1 Jul 2012
Pierce Brandon L, Tong Lin, Kraft Peter, Ahsan Habibul
Abstract excerpt
Genome-wide association (GWA) studies have identified several pancreatic cancer (PanCa) susceptibility loci. Methods for assessment of polygenic susceptibility can be employed to detect the collective effect of additional association signals for PanCa. Using data on 492,651 autosomal single nucleotide polymorphisms (SNPs) from the PanScan GWA study (2,857 cases, 2,967 controls), we employed polygenic risk score...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
