Article
[Polymorphic variants of genes encoding interleukin-6 and fibrinogen, the risk of ischemic stroke and fibrinogen levels].
Molekuliarnaia biologiia - 1 Jan 2000
Titov B V, Barsova R M, Martynov M Iu, Nikonova A A, Favorov A V, Gusev E I, Favorova O O
Abstract excerpt
Carriage frequencies of alleles and genotypes of polymorphous locus of -174G>C IL6 (rs1800795) were analyzed in the patients with ischemic stroke (IS) of Russian ethnic descent (200 cases) and in the control group of the same ethnic descent with similar sex and age (140 controls). Significant differences were identified in frequencies of carriage (in homo- or heterozygous form) of allele IL6*-174G (p = 0.0029, OR...
Topics
- Aged
- Female
- Fibrinogen
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans