Article
[Allele frequency distributions of -174G/C polymorphism in regulatory region of interleukin 6 gene (IL6) in Russian and worldwide populations].
Genetika - 1 Jan 2013
Borinskaya S A, Gureev A S, Orlova A A, Sanina E D, Kim A A, Gasemianrodsari F, Shirmanov V I, Balanovsky O P, Rebrikov D V, Koshechkin A V, Yankovsky N K
Abstract excerpt
Allele and genotype frequencies of the -174G/C polymorphism (rs1800795) in the regulatory region of the IL6 gene, which encode anti-inflammatory cytokine interleukin 6, were determined in seven populations representing five ethnic groups from the European part of Russia (440 individuals), as well as in small cohorts that represent populations from 24 countries of Africa and Eurasia (365 individuals). The maps of...
Topics
- Environment
- Gene Frequency
- HapMap Project
- Humans
- Interleukin-6
- Polymorphism, Single Nucleotide
- Regulatory Sequences, Nucleic Acid