Article
Cellular fatty acid uptake: a pathway under construction.
Trends in endocrinology and metabolism: TEM - 1 Mar 2009
Su Xiong, Abumrad Nada A
Abstract excerpt
Membrane uptake of long-chain fatty acids (FAs) is the first step in cellular FA utilization and a point of metabolic regulation. CD36 facilitates a major fraction of FA uptake by key tissues. This review highlights the contribution of CD36 to pathophysiology in rodents and humans. Novel concepts regarding regulation of CD36-facilitated uptake are discussed (i.e. the role of membrane rafts and caveolae, CD36...
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